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| Oliveira,Lara Alexandre de; Souza-Moreira,Tatiana Maria de; Cefali,Letícia Caramori; Chiari,Bruna Galdorfini; Corrêa,Marcos Antonio; Isaac,Vera Lucia Borges; Salgado,Hérida Regina Nunes; Pietro,Rosemeire Cristina Linhari Rodrigues. |
| The leaves of the Brazilian species Plinia cauliflora were used to obtain active hydroalcoholic extract and fractions enabling the development of efficient antiseptic pharmaceutical formulations. A chemical composition of 70% ethanol extract, aqueous and ethyl acetate fractions was analyzed by thin-layer chromatography and for phenol content. Antimicrobial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Lactobacillus acidophilus and Candida albicans by the agar diffusion method and the minimum inhibitory concentration was assayed by broth microdilution. Extract microbiological quality was tested to avoid contamination in the formulations. A mouthwash and a topical cream containing the extract were developed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Antiseptic formulations/design; Plinia cauliflora/antimicrobial activity; Plinia cauliflora/antiseptic activity; Mouthwash; Plant extract; Topical cream. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000300010 |
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| Paula,Isabela Moreira Baumgratz de; Moraes,Flávia Costa; Souza,Orlando Vieira de; Yamamoto,Célia Hitomi. |
| Rosmarinus officinalis, which belongs to the Lamiaceaefamily, is a species of medicinal flora with therapeutic properties. In order to exploit the benefits of these properties, a mouthwash formulation was developed, with careful selection of raw materials to meet pharmacotechnical requirements. Extracts of the plant were incorporated into a mouthwash, which was shown to have inhibitory action in vitro against the micro-organisms commonly found in periodontics. Controls for assessing the quality of the drugs were carried out, quantifying phenols and flavonoids as chemical markers. Mouthwash solutions were formulated containing 0.1, 5 and 10% ethanol extract of R. officinalis; and 0.05, 5 and 10% of the hexane fraction of R. officinalis. In order to evaluate... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rosmarinus officinalis/pharmacognosy; Rosmarinus officinalis/Anti-microbial activity; Mouthwash; Periodontics/use of mouthwash; Medicinal plants. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400851 |
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| Bernardi,R.; Perin,C.; Becker,F.L.; Ramos,G.Z.; Gheno,G.Z.; Lopes,L.R.; Pires,M.; Barros,H.M.T.. |
| Pilocarpine is a cholinergic agonist that increases salivary flow and has been used to treat xerostomia. Oral intake is the most frequent route of administration. Adverse effects are dose-dependent and include sudoresis, facial blushing and increased urinary frequency. The objective of the present study was to evaluate the effects of topical pilocarpine solutions as mouthwashes on salivary flow and their adverse effects on healthy subjects. Forty volunteers received 10 ml 0.5, 1 and 2% pilocarpine solutions or 0.9% saline in a randomized, double-blind, placebo-controlled manner. Salivation was measured before and 45, 60 and 75 min after mouth rinsing for 1 min with 10 ml of saline or pilocarpine solutions. Vital signs were measured and ocular,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pilocarpine; Mouth rinsing; Mouthwash; Xerostomia; Salivation. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100015 |
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